IR Home
DAO
Home
Editors
Forthcoming
Information
Journals
Home
MEPS
AME
CR
DAO
ESEP
Search
Subscribe
Book Series
EE Books
Top Books
Order
Discussion Forums
Home
Research
Endangered Species Programs
Institutions
International Ecology Institute
Eco-Ethics International Union
Foundation
Otto Kinne Foundation
| |
DAO 49:19-25 (2001)
|
Abstract
|
A syntenin-like protein with postsynaptic density protein (PDZ) domains produced by black tiger shrimp Penaeus monodon in response to white spot syndrome virus infection
Phuwadol Bangrak1, Potchanapond Graidist
2, Wilaiwan Chotigeat1, Kidchakan Supamattaya
3, Amornrat Phongdara
1,*
1 Department of Biochemistry, Faculty of Science, Prince of Songkla University, Hat-Yai, Songkhla 90110, Thailand
2 Department of Biotechnology, Faculty of Agro-Industry, Prince of Songkla University, Hat-Yai, Songkhla 90110, Thailand
3 Department of Aquatic Science, Faculty of Natural Resources, Prince of Songkla University, Hat-Yai, Songkhla 90110, Thailand
*Corresponding author. E-mail: pamornra@ratree.psu.ac.th
ABSTRACT: We report the isolation and characterization of products from a subtractive cDNA library from the haemolymph of Penaeus monodon experimentally infected with white spot syndrome virus (WSSV). One cDNA derived from up-regulated mRNA was
identified. A homology search indicated similarity to the putative protein syntenin (TE8). The nearly complete nucleotide sequence of TE8 was obtained by rapid amplification of cDNA (RACE). Its putative protein product contained a tandem repeat of PDZ
domains (postsynaptic density protein or PSD-95, DlgA and ZO-1). We propose that TE8 may function as an adapter that couples PDZ-binding protein(s) in a signaling pathway involved in the shrimp response to WSSV.
KEY WORDS: White spot syndrome virus · Penaeus monodon · Signal transduction · Syntenin · Postsynaptic density protein · PDZ
Full text in pdf format
Published in DAO Vol.
49, No. 1
(2001) on December 20
Print ISSN: 0177-5103; Online ISSN: 1616-1580.
Copyright © Inter-Research, Oldendorf/Luhe, 2001
|
